Description

α-Bromo-4-Hydroxy-3,5-Dinitroacetophenone is a specialized brominated and nitrated acetophenone derivative, serving as a versatile and reactive synthetic intermediate. Its unique structure, featuring both bromo and nitro substituents on an aromatic ketone, makes it a valuable precursor for constructing complex molecules in advanced organic synthesis. This high-purity intermediate is primarily sought by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and other crop protection agents.
• Organic Synthesis Reagent: Acts as a reactive electrophile in nucleophilic aromatic substitution and cross-coupling reactions.
• Dye and Pigment Precursor: Serves as an intermediate in the manufacture of specialized nitro- and bromo-substituted colorants.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Item	Details
Product Name	α-Bromo-4-Hydroxy-3,5-Dinitroacetophenone
CAS No.	120388-18-3
Molecular Formula	C8H5BrN2O6
Molecular Weight	305.04 g/mol
Synonyms	2-Bromo-1-(4-hydroxy-3,5-dinitrophenyl)ethanone; 4'-Hydroxy-3',5'-dinitro-2-bromoacetophenone; 1-(4-Hydroxy-3,5-dinitrophenyl)-2-bromoethanone; α-Bromo-4-hydroxy-3,5-dinitroacetophenone; Bromo(4-hydroxy-3,5-dinitrophenyl)methanone (related); 2-Bromo-4'-hydroxy-3',5'-dinitroacetophenone
EINECS	Contact for details

Quality Control

Our α-Bromo-4-Hydroxy-3,5-Dinitroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.