Description

1H-Pyrazole-3-Carbonitrile,5-Amino-1-[2,6-Dichloro-4-Trifluoromethyl)Phenyl]-4-(Ethylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the agrochemical and pharmaceutical sectors. Industrial-scale manufacturers and R&D organizations require this material for developing next-generation crop protection agents and specialized therapeutic compounds, where its unique trifluoromethylphenyl and ethylsulfonyl pyrazole structure provides key biological activity.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern pesticides and herbicides, leveraging its pyrazole core for targeted biological action.
• Pharmaceutical API Synthesis: Used as a sophisticated building block for constructing novel drug candidates, especially in areas requiring fluorinated motifs.
• Chemical Research & Development: Serves as a valuable substrate for method development and exploring new reactions in medicinal and synthetic chemistry.
• Specialty Fine Chemical Production: Employed in the manufacture of other high-value, complex organic molecules for various industrial applications.

Basic Information

Product Name	1H-Pyrazole-3-Carbonitrile,5-Amino-1-[2,6-Dichloro-4-Trifluoromethyl)Phenyl]-4-(Ethylsulfonyl)-
CAS No.	120068-68-0
Molecular Formula	C13H9Cl2F3N4O2S
Molecular Weight	413.20 g/mol
Synonyms	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(ethylsulfonyl)-1H-pyrazole-3-carbonitrile; Fipronil Intermediate; Fipronil Metabolite; Fipronil Derivative; 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-ethylsulfonyl-1H-pyrazole-3-carbonitrile; 1H-Pyrazole-3-carbonitrile, 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfonyl)-; 120068-68-0
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-3-Carbonitrile,5-Amino-1-[2,6-Dichloro-4-Trifluoromethyl)Phenyl]-4-(Ethylsulfonyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthesis. All material is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.