Description

Methyl cis-2-Aminocyclopentanecarboxylate Hydrochloride is a high-purity chiral building block essential for advanced pharmaceutical synthesis and organic chemistry research. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Peptidomimetic Chemistry: Used in the construction of conformationally constrained peptide analogs and protease inhibitors.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric transformations to introduce the cyclopentane scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for various biological targets.
• Fine Chemical Production: Integral in the multi-step synthesis of specialty chemicals and advanced materials requiring high stereochemical purity.

Basic Information

Product Name	Methyl cis-2-Aminocyclopentanecarboxylate Hydrochloride
CAS No.	119993-55-4
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	Methyl (1R,2S)-2-Aminocyclopentanecarboxylate Hydrochloride; Methyl cis-2-Aminocyclopentanecarboxylate HCl; cis-2-(Methoxycarbonyl)cyclopentylamine Hydrochloride; (1R,2S)-2-(Methoxycarbonyl)cyclopentan-1-amine Hydrochloride; Methyl 2-Amino-1-cyclopentanecarboxylate Hydrochloride (cis); Cyclopentanecarboxylic acid, 2-amino-, methyl ester, hydrochloride, (1R,2S)-rel-; Aminocyclopentanecarboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl cis-2-Aminocyclopentanecarboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.