Description

(R)-2-tert-Butyl-3-Methyl-4-Oxoimidazolidin-1-Ium (R)-2-Hydroxy-2-Phenylacetate CAS NO 119838-37-8 is a high-purity chiral ionic salt, specifically designed as a key intermediate in advanced organic synthesis. This compound is valued for its role in facilitating stereoselective reactions, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists and production units in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in neurology and cardiology drug candidates.
• Chiral Auxiliary/ Catalyst Precursor: Used in asymmetric synthesis to induce chirality in target molecules, improving yield and purity of desired stereoisomers.
• Agrochemical Synthesis: Intermediate in the production of advanced, stereospecific herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where specific chirality is required for functionality.
• Academic & Industrial R&D: Serves as a valuable reagent for method development and exploration of new synthetic pathways in organic chemistry laboratories.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of chiral compounds.

Basic Information

Product Name	(R)-2-tert-Butyl-3-Methyl-4-Oxoimidazolidin-1-Ium (R)-2-Hydroxy-2-Phenylacetate
CAS No.	119838-37-8
Molecular Formula	C₁₆H₂₂N₂O₄
Molecular Weight	306.36 g/mol
Synonyms	(R)-2-tert-Butyl-3-methyl-4-oxoimidazolidin-1-ium (R)-2-hydroxy-2-phenylacetate; (R)-2-(tert-Butyl)-3-methyl-4-oxoimidazolidin-1-ium (R)-mandelate; (R)-TBMI Mandelate Salt; (R)-tert-Butylmethylimidazolidinone mandelate; Chiral imidazolidinone mandelate salt; (R)-2-tert-Butyl-3-methyl-1,3-diazolidin-4-one (R)-mandelate; Evans Auxiliary Derivative Salt
EINECS	Contact for details

Quality Control

Our (R)-2-tert-Butyl-3-Methyl-4-Oxoimidazolidin-1-Ium (R)-2-Hydroxy-2-Phenylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and elemental analysis, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.