Description

2-(1-Adamantyl)Quinoline-4-Carboxylic Acid is a high-value, structurally complex organic compound featuring a rigid adamantane moiety fused to a quinoline carboxylic acid core. This unique architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies and library synthesis due to its adamantyl group's influence on lipophilicity and metabolic stability.
• Agrochemical Development: Employed in the research and synthesis of new-generation pesticides and herbicides, where the adamantane structure can enhance biological activity and environmental persistence.
• Ligand and Catalyst Synthesis: Acts as a starting material for creating specialized ligands used in catalytic processes or as components in metal-organic frameworks (MOFs).
• Advanced Material Precursor: Utilized in the development of organic electronic materials, such as charge-transport layers or luminescent compounds, due to its conjugated quinoline system.
• Chemical Biology Probes: Functionalized to create molecular probes for studying biological pathways and enzyme functions in academic and industrial research settings.

Basic Information

Product Name	2-(1-Adamantyl)Quinoline-4-Carboxylic Acid
CAS No.	119778-65-3
Molecular Formula	C20H21NO2
Molecular Weight	307.39 g/mol
Synonyms	2-(1-Adamantyl)-4-quinolinecarboxylic acid; 2-Adamantan-1-ylquinoline-4-carboxylic acid; 2-Tricyclo[3.3.1.1³,⁷]dec-1-ylquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 2-(1-adamantyl)-; Adamantylquinolinecarboxylic acid; AQCA; 2-(Adamantan-1-yl)quinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(1-Adamantyl)Quinoline-4-Carboxylic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong acids and oxidizing agents. For long-term storage, consider inert atmosphere packaging to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.