Description

2-Amino-7,7-Dimethyl-2',5-Dioxo-1',2',5,6,7,8-Hexahydrospiro[Chromene-4,3'-Indole]-3-Carbonitrile is a high-value, structurally complex heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its unique spirocyclic framework and functional group diversity make it an essential building block for creating novel molecular architectures with targeted properties. This compound is primarily sought after by research institutions and industrial R&D departments focused on developing new pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its complex indole-chromene fused structure.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its spirocyclic core can contribute to unique modes of action and improved environmental profiles.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a sophisticated building block for creating electron-transport or host materials in OLED displays and lighting, leveraging its rigid, conjugated structure.
• Dye and Pigment Synthesis: Acts as an intermediate for synthesizing specialized chromophores and high-performance pigments with enhanced lightfastness and color properties.
• Academic & Contract Research: Employed in methodological studies and as a model substrate for developing new catalytic reactions (e.g., C-H activation, spirocyclization) in university and CRO laboratories.
• Material Science: Investigated for incorporation into polymers or metal-organic frameworks (MOFs) to impart specific thermal or optical characteristics.

Basic Information

Product Name	2-Amino-7,7-Dimethyl-2',5-Dioxo-1',2',5,6,7,8-Hexahydrospiro[Chromene-4,3'-Indole]-3-Carbonitrile
CAS No.	119771-51-6
Molecular Formula	C20H17N3O3
Molecular Weight	347.37 g/mol
Synonyms	2-Amino-7,7-dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydrospiro[chromene-4,3'-indole]-3-carbonitrile; 3-Cyano-2-amino-7,7-dimethyl-1',2',5,6,7,8-hexahydrospiro[4H-chromene-4,3'-indoline]-2',5-dione; Spiro[chromene-4,3'-indole]-3-carbonitrile, 2-amino-1',2',5,6,7,8-hexahydro-7,7-dimethyl-2',5-dioxo-; 119771-51-6; 2-Amino-7,7-dimethyl-5-oxo-1,2,5,6,7,8-hexahydrospiro[chromene-4,3'-indole]-2'-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-7,7-Dimethyl-2',5-Dioxo-1',2',5,6,7,8-Hexahydrospiro[Chromene-4,3'-Indole]-3-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical data is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.