Description

β-Hydroxy-α-Phenyl-(1,1'-Biphenyl)-4-Propanoic Acid, (R',R')-(+)- CAS NO 119725-33-6 is a high-purity, single-enantiomer chiral compound belonging to the class of biphenyl-substituted propanoic acids. This product matters for its role as a critical chiral intermediate or building block in the synthesis of advanced pharmaceutical active ingredients and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high stereochemical purity for developing new drugs and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), receptor antagonists, and other active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Used in the development of chiral catalysts or ligands for enantioselective reactions in fine chemical production.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, or plant growth regulators with specific stereochemical activity.
• Material Science Research: Potential monomer or additive for creating chiral polymers or liquid crystalline materials with specialized optical properties.
• Academic & Industrial R&D: Serves as a reference standard or starting material for method development and novel synthetic route exploration in organic chemistry.

Basic Information

Product Name	β-Hydroxy-α-Phenyl-(1,1'-Biphenyl)-4-Propanoic Acid, (R',R')-(+)-
CAS No.	119725-33-6
Molecular Formula	C21H18O3
Molecular Weight	318.37 g/mol
Synonyms	(R,R)-(+)-2-Hydroxy-2-phenyl-3-(4-biphenylyl)propionic Acid; (R,R)-(+)-2-Hydroxy-2-phenyl-3-(biphenyl-4-yl)propanoic Acid; (+)-(R,R)-2-Hydroxy-2-phenyl-3-(4-phenylphenyl)propanoic Acid; (R',R')-(+)-β-Hydroxy-α-Phenyl-(1,1'-Biphenyl)-4-Propanoic Acid; (R,R)-Biphenyl-4-yl(phenyl)lactic acid; (R,R)-2-Hydroxy-3-(4-biphenylyl)-2-phenylpropionic Acid; (R,R)-2-Hydroxy-2-phenyl-3-[1,1'-biphenyl]-4-yl-propanoic acid
EINECS	Contact for details

Quality Control

Our β-Hydroxy-α-Phenyl-(1,1'-Biphenyl)-4-Propanoic Acid, (R',R')-(+)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure. Keep the container tightly sealed when not in use to protect integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.