Description

(S)-(-)-3,3'-Dibromo-1,1'-Bi-2-Naphthol CAS NO 119707-74-3 is a high-purity, chiral binaphthol derivative characterized by its axial chirality and bromine substituents. This compound is a critical chiral ligand and building block in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in catalytic processes and molecular design.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand for metal-catalyzed asymmetric reactions, including C-C bond formations and oxidations.
• Pharmaceutical Intermediates: A key precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Chiral Resolution: Used in the preparation of chiral stationary phases for HPLC to separate enantiomers.
• Material Science: Employed as a monomer or dopant for creating chiral polymers and advanced optical materials.
• Agrochemical Synthesis: Facilitates the production of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable tool for method development and discovery chemistry in laboratories worldwide.

Basic Information

Product Name	(S)-(-)-3,3'-Dibromo-1,1'-Bi-2-Naphthol
CAS No.	119707-74-3
Molecular Formula	C₂₀H₁₂Br₂O₂
Molecular Weight	444.12 g/mol
Synonyms	(S)-(-)-3,3'-Dibromo-1,1'-Bi-2-naphthol; (S)-3,3'-Dibromo-1,1'-binaphthyl-2,2'-diol; (S)-(-)-3,3'-Dibromo-BINOL; (S)-BINOL-3,3'-dibromide; (S)-(-)-3,3'-Dibromo-2,2'-dihydroxy-1,1'-binaphthyl; (S)-(-)-3,3'-Dibromobinaphthol; (S)-(-)-3,3'-Dibromo-1,1'-binaphthalene-2,2'-diol; (S)-(-)-3,3'-Dibromo-1,1'-binaphthyl-2,2'-diol
EINECS	Contact for details

Quality Control

Our (S)-(-)-3,3'-Dibromo-1,1'-Bi-2-Naphthol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity verification, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and chiral integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.