Description

8-Fluoro-Quinazoline-2,4-Diamine is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential herbicidal or fungicidal properties.
• Material Science: Potential use in the synthesis of specialty chemicals, dyes, or organic electronic materials due to its fused heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	8-Fluoro-Quinazoline-2,4-Diamine
CAS No.	119584-79-1
Molecular Formula	C9H8FN5
Molecular Weight	205.19 g/mol
Synonyms	8-Fluoro-2,4-quinazolinediamine; 2,4-Diamino-8-fluoroquinazoline; 8-Fluoroquinazoline-2,4-diyldiamine; Quinazoline-2,4-diamine, 8-fluoro-; 119584-79-1; 8-Fluoro-2,4-diaminoquinazoline; 8-Fluoro-2,4-diamino-quinazoline
EINECS	Contact for details

Quality Control

Our 8-Fluoro-Quinazoline-2,4-Diamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality management system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.