Description

5-Bromo-Quinazoline-2,4-Diamine is a high-purity, halogenated quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of pharmaceutical candidates, particularly kinase inhibitors and other biologically active molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific bromine and amine functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted therapeutic agents, including potential tyrosine kinase inhibitors for oncology research.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the quinazoline scaffold's bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and signal transduction pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.
• Material Science Research: Investigated as a monomer or precursor for constructing organic electronic materials and advanced polymers.

Basic Information

Product Name	5-Bromo-Quinazoline-2,4-Diamine
CAS No.	119584-75-7
Molecular Formula	C8H7BrN4
Molecular Weight	239.08 g/mol
Synonyms	2,4-Diamino-5-bromoquinazoline; 5-Bromo-2,4-diaminoquinazoline; 5-Bromoquinazoline-2,4-diamine; 5-Bromo-2,4-quinazolinediamine; Quinazoline, 2,4-diamino-5-bromo-; 119584-75-7; 5-Br-QDA
EINECS	Contact for details

Quality Control

Our 5-Bromo-Quinazoline-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.