Description

3-Iododizocilpine is a high-purity, iodinated derivative of dizocilpine (MK-801), a well-known non-competitive NMDA receptor antagonist. This compound is a critical research-grade chemical, valued for its utility in advanced neuroscience and pharmacological studies. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on developing and studying neurological pathways and receptor mechanisms.

Application

• Neuroscience Research: Used as a potent, iodinated tool compound for studying NMDA receptor function and glutamatergic signaling pathways.
• Pharmacological Probe Development: Serves as a key intermediate or reference standard in the development of novel neuroprotective agents or CNS-targeting pharmaceuticals.
• Biochemical Assays: Employed in receptor binding studies, autoradiography, and other in vitro assays to investigate ion channel activity and inhibition.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in research and pre-clinical settings.
• Chemical Synthesis: Acts as a specialized building block for the synthesis of more complex molecules designed for neurological research.

Basic Information

Product Name	3-Iododizocilpine
CAS No.	119508-63-3
Molecular Formula	C16H15IN2
Molecular Weight	386.21 g/mol
Synonyms	3-Iodo-MK-801; 3-Iododizocilpine Maleate; 3-Iodo-(5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine; 3-Iodo-(+)-MK-801; 3-I-MK-801; 3-Iododizocilpine (MK-801 derivative); 3-Iodo-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine
EINECS	Contact for details

Quality Control

Our 3-Iododizocilpine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance in sensitive experimental models.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.