Description

Galili Pentasaccharide is a specific, well-defined carbohydrate structure of significant interest in biomedical research and development. This compound matters as a key synthetic antigen for studying and targeting human anti-Gal antibodies, which play a crucial role in xenotransplantation and cancer immunotherapy. It is primarily needed by research institutions, diagnostic developers, and pharmaceutical companies focused on immunology, glycobiology, and the development of novel therapeutic and diagnostic platforms. Galili Pentasaccharide CAS NO 119502-59-9 represents a high-purity standard for critical immunological studies.

Application

• Immunological Research: Used as a defined antigen to study the binding and function of natural anti-Gal (α-Gal) antibodies in human serum.
• Xenotransplantation Studies: Serves as a critical tool in research aimed at overcoming hyperacute rejection in pig-to-human organ transplants by characterizing antibody-antigen interactions.
• Cancer Vaccine Development: Investigated as a component in vaccine strategies designed to elicit an immune response against cancer cells expressing α-Gal epitopes.
• Diagnostic Reagent Manufacturing: Employed in the production of immunoassays and diagnostic kits for the detection and quantification of anti-Gal antibodies.
• Glycobiology & Biochemistry: Acts as a reference standard and building block for synthesizing more complex glycoconjugates and studying carbohydrate-protein interactions.
• Biopharmaceutical Development: Utilized in the characterization and quality control of therapeutic proteins and antibodies where glycosylation patterns are critical.

Basic Information

Product Name	Galili Pentasaccharide
CAS No.	119502-59-9
Molecular Formula	C26H43NO21
Molecular Weight	681.62 g/mol
Synonyms	Galα1-3Galβ1-4GlcNAcβ1-3Galβ1-4Glc; α-Gal Pentasaccharide; Galili antigen; Anti-Gal antigen; Bdihexaose, O-α-D-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-D-glucopyranose; GBG-185; 119502-59-9; α-D-Galp-(1→3)-β-D-Galp-(1→4)-β-D-GlcpNAc-(1→3)-β-D-Galp-(1→4)-D-Glcp
EINECS	Contact for details

Quality Control

Our Galili Pentasaccharide is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization including HPLC for purity, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.