Description

Dl-Phenylalanine-Obzl p-Tosylate CAS NO 119290-61-8 is a protected derivative of phenylalanine, a crucial amino acid building block. This compound serves as a key chiral intermediate in the synthesis of complex peptides and pharmaceutical active ingredients, offering controlled reactivity for advanced chemical transformations. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce phenylalanine residues with orthogonal protecting groups.
• Protecting Group Strategy: The Obzl (benzyl ester) and p-Tosylate groups provide specific deprotection pathways, enabling complex multi-step synthetic sequences.
• Chiral Pool Synthesis: Serves as a source of chirality for the asymmetric synthesis of non-proteinogenic amino acids and other chiral compounds.
• Bioconjugation & Labeling: Potential use in the modification of peptides and proteins for diagnostic or therapeutic purposes.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for hit-to-lead optimization and the development of new chemical entities.

Basic Information

Product Name	Dl-Phenylalanine-Obzl p-Tosylate
CAS No.	119290-61-8
Molecular Formula	C23H23NO5S
Molecular Weight	425.50 g/mol
Synonyms	DL-Phenylalanine benzyl ester p-toluenesulfonate salt; Benzyl DL-phenylalaninate 4-methylbenzenesulfonate; Phenylalanine, benzyl ester, dl-, 4-methylbenzenesulfonate; H-DL-Phe-OBzl.TosOH; (RS)-2-Amino-3-phenylpropionic acid benzyl ester p-toluenesulfonic acid salt; DL-Phenylalanine benzyl ester tosylate; Benzyl DL-α-aminohydrocinnamate p-toluenesulfonate
EINECS	Contact for details

Quality Control

Our Dl-Phenylalanine-Obzl p-Tosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. Specifications can be aligned with research-grade or GMP-starting material standards based on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (approx. 50:50)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.