Description

Besipirdine is a selective, high-affinity ligand for neuronal imidazoline receptors, primarily investigated for its potential neuroprotective and cognitive-enhancing properties. This compound is of significant interest in advanced pharmaceutical research and development, particularly for targeting neurodegenerative pathways. It is utilized by research institutions and pharmaceutical companies engaged in neuroscience, drug discovery, and the development of novel therapeutic agents for conditions like Alzheimer's disease.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in preclinical studies for neurological disorders.
• Neuroscience Studies: Used as a pharmacological tool to investigate the role of imidazoline I2 receptors in cognitive function, neuroprotection, and behavior.
• Drug Discovery Programs: Acts as a lead compound or intermediate in the synthesis of novel molecules targeting central nervous system (CNS) diseases.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening assays for receptor binding studies.
• Academic Research: Utilized in university and institutional labs for fundamental research on receptor pharmacology and signal transduction.
• GMP Manufacturing: Supplied as a high-purity intermediate for cGMP-compliant production of investigational new drugs (INDs).

Basic Information

Product Name	Besipirdine
CAS No.	119257-34-0
Molecular Formula	C17H19N3O
Molecular Weight	281.35 g/mol
Synonyms	Besipirdine Hydrochloride; BSP; 4-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-1H-imidazole; HP 749; HP-749; 1H-Imidazole, 4-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-; UNII-2QZ1K7S4L1
EINECS	Contact for details

Quality Control

Our Besipirdine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.