Description

Dibenz(A,J)Anthracene-3,4-Diol-1,2-Epoxide (CAS NO 119181-08-7) is a high-purity, polycyclic aromatic hydrocarbon (PAH) metabolite and a critical reference standard in advanced chemical and biological research. This compound is of significant value for its role in studying metabolic activation pathways, DNA adduct formation, and the mechanisms of chemical carcinogenesis. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in toxicology, environmental monitoring, and cancer research.

Application

• Toxicological Research: Used as a reference standard in studies investigating the metabolic activation and carcinogenic potential of polycyclic aromatic hydrocarbons (PAHs).
• Biomarker Analysis: Essential for the development and validation of analytical methods (e.g., HPLC, GC-MS) to detect and quantify DNA adducts in biological samples.
• Environmental Monitoring: Serves as a key analyte in assessing human exposure to complex environmental pollutants and occupational hazards.
• Pharmaceutical Development: Employed in mechanistic studies to understand drug-induced genotoxicity and to support safety assessments.
• Academic Research: A vital tool in biochemistry and molecular biology laboratories for fundamental research on mutagenesis and DNA repair mechanisms.
• Quality Control & Method Development: Used by analytical service providers and contract research organizations (CROs) to calibrate instruments and ensure assay accuracy.

Basic Information

Product Name	Dibenz(A,J)Anthracene-3,4-Diol-1,2-Epoxide
CAS No.	119181-08-7
Molecular Formula	C22H14O3
Molecular Weight	326.35 g/mol
Synonyms	DB[a,j]A-3,4-diol-1,2-epoxide; 1,2-Epoxy-3,4-dihydroxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene; Anti-DB[a,j]A-3,4-diol-1,2-epoxide; Dibenz[a,j]anthracene 3,4-dihydrodiol 1,2-epoxide; (±)-anti-1,2,3,4-Tetrahydro-1,2-epoxy-3,4-dihydroxydibenz[a,j]anthracene; PAH Metabolite Standard; Dibenzanthracene Diol Epoxide
EINECS	Contact for details

Quality Control

Our Dibenz(A,J)Anthracene-3,4-Diol-1,2-Epoxide is produced and handled under strict quality protocols to ensure batch-to-batch consistency and integrity for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC purity analysis and structural confirmation (NMR, MS). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chromatographic data is provided with every shipment to support your compliance and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time matches reference standard
Identification (MS)	Mass spectrum conforms
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, Acetone

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.