Description

Pyroglutamic Acid, 4-Methyl-, Hydrazide (6Ci) is a specialized heterocyclic building block and derivative of pyroglutamic acid, featuring a reactive hydrazide functional group. This compound is valued for its role as a key synthetic intermediate in the preparation of more complex molecules, particularly in pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Peptidomimetic Research: Used to create constrained peptide analogs and protease inhibitors due to its pyroglutamate backbone and reactive handle.
• Agrochemical Synthesis: Acts as a building block for developing new active ingredients with herbicidal or fungicidal properties.
• Ligand and Catalyst Development: Employed in the design of chiral ligands for asymmetric catalysis or metal-chelating agents.
• Bioconjugation Chemistry: The hydrazide group facilitates selective coupling reactions with aldehydes and ketones for labeling or linker attachment.
• Academic & Institutional Research: Utilized in chemical biology and medicinal chemistry programs for exploring new chemical space and structure-activity relationships.

Basic Information

Product Name	Pyroglutamic Acid, 4-Methyl-, Hydrazide (6Ci)
CAS No.	119074-74-7
Molecular Formula	C6H11N3O2
Molecular Weight	157.17 g/mol
Synonyms	4-Methyl-5-oxopyrrolidine-2-carbohydrazide; (4S)-4-Methyl-5-oxo-D-proline hydrazide; 4-Methyl-D-pyroglutamic hydrazide; L-4-Methylpyroglutamic acid hydrazide; 4-Methylpyroglutamylhydrazide; (S)-4-Methyl-2-pyrrolidone-5-carboxylic acid hydrazide; 5-Oxo-4-methylproline hydrazide
EINECS	Contact for details

Quality Control

Our Pyroglutamic Acid, 4-Methyl-, Hydrazide (6Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.