Description

1-Bromo-4-(2-Methoxypropan-2-yl)benzene is a high-purity aromatic bromo compound featuring a tertiary butyl ether moiety, serving as a versatile and valuable synthetic intermediate. Its unique structure makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in drug discovery, ligand synthesis, and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzene core with specific steric and electronic properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromine atom allows for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its aromatic and ether functionalities.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex organic frameworks in medicinal and synthetic chemistry programs.

Basic Information

Item	Detail
Product Name	1-Bromo-4-(2-Methoxypropan-2-yl)benzene
CAS No.	119027-36-0
Molecular Formula	C11H15BrO
Molecular Weight	243.14 g/mol
Synonyms	4-Bromo-α,α-dimethylbenzyl methyl ether; 1-Bromo-4-(2-methoxy-2-propyl)benzene; 2-(4-Bromophenyl)-2-methoxypropane; p-Bromo-α,α-dimethylbenzyl methyl ether; 4-Bromo-α,α-dimethylbenzenemethanol methyl ether; (4-Bromophenyl)(1-methoxy-1-methylethyl)methane; 2-(4-Bromophenyl)-2-methoxypropane
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-4-(2-Methoxypropan-2-yl)benzene adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical specifications. Our quality system is designed to meet the rigorous standards required for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.