Description

Benzyl 2-(Aminomethyl)Pyrrolidine-1-Carboxylate Hydrochloride is a high-purity chemical building block and intermediate of significant importance in advanced organic synthesis. This compound is valued for its pyrrolidine scaffold and protected amine functionality, which are critical for constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Peptidomimetic Research: Used to introduce constrained pyrrolidine structures into peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with specific mode-of-action profiles.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal complexes.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	Benzyl 2-(Aminomethyl)Pyrrolidine-1-Carboxylate Hydrochloride
CAS No.	119020-00-7
Molecular Formula	C13H19ClN2O2
Molecular Weight	270.75 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-2-(aminomethyl)pyrrolidine hydrochloride; Cbz-2-(Aminomethyl)pyrrolidine Hydrochloride; (2-Aminomethyl-1-pyrrolidine)carboxylic Acid Benzyl Ester Hydrochloride; N-Cbz-2-(Aminomethyl)pyrrolidine HCl; 2-(Aminomethyl)-1-pyrrolidinecarboxylic Acid Phenylmethyl Ester Hydrochloride; 1-Carbobenzyloxy-2-aminomethylpyrrolidine Hydrochloride; Benzyl N-(2-Aminomethylpyrrolidin-1-yl)formate Hydrochloride
EINECS	Contact for details

Quality Control

Our Benzyl 2-(Aminomethyl)Pyrrolidine-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications in research and cGMP-compliant development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.