Description

4-Methanesulfonyl-2-(Trifluoromethyl)Benzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both a methanesulfonyl and a trifluoromethyl group, makes it an exceptionally valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty monomers and polymers, contributing to materials with specific thermal, chemical, or surface properties.
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its electron-withdrawing substituents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) developing proprietary compounds.

Basic Information

Product Name	4-Methanesulfonyl-2-(Trifluoromethyl)Benzoic Acid
CAS No.	118939-17-6
Molecular Formula	C9H7F3O4S
Molecular Weight	268.21 g/mol
Synonyms	2-(Trifluoromethyl)-4-(methylsulfonyl)benzoic acid; 4-(Methylsulfonyl)-2-(trifluoromethyl)benzoic acid; Benzoic acid, 4-(methylsulfonyl)-2-(trifluoromethyl)-; 4-Methanesulphonyl-2-trifluoromethylbenzoic acid; 4-Mesyl-2-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Methanesulfonyl-2-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with industry best practices for advanced intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.