Description

2,4,7,8,9-Pentaacetyl-D-n-Acetylglycolylneuraminic Acid Methyl Ester is a key protected derivative of sialic acid, a critical carbohydrate building block in glycobiology research and pharmaceutical development. This high-purity intermediate is essential for the controlled synthesis of complex glycoconjugates, enabling precise structural studies and the creation of novel bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors focused on glycoscience, antiviral drug discovery, and vaccine development.

Application

• Glycoconjugate Synthesis: A crucial protected intermediate for the chemical and enzymatic synthesis of sialylated oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Intermediates: Serves as a key building block in the research and development of sialidase inhibitors, antiviral agents, and anti-inflammatory drugs.
• Biochemical Research: Used in enzymatic studies, receptor-ligand interaction assays, and the investigation of sialic acid-mediated biological processes.
• Diagnostic Reagent Development: Employed in the production of standards and reagents for assays detecting sialic acid levels or specific glycosylation patterns.
• Vaccine Adjuvant Research: Investigated for its potential role in the design of novel carbohydrate-based vaccine components and adjuvants.
• Glycoengineering: A valuable tool for chemoenzymatic remodeling of cell surfaces and proteins to study or alter their biological functions.

Basic Information

Item	Detail
Product Name	2,4,7,8,9-Pentaacetyl-D-n-Acetylglycolylneuraminic Acid Methyl Ester
CAS No.	118865-38-6
Molecular Formula	C28H41NO20
Molecular Weight	687.62 g/mol
Synonyms	Methyl 5-acetamido-2,4,7,8,9-penta-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonate; Methyl 5-acetamido-2,4,7,8,9-penta-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonate; Pentaacetyl Neu5Ac Methyl Ester; N-Acetylneuraminic Acid Methyl Ester Pentaacetate; Sialic Acid Methyl Ester Pentaacetate; Neu5Ac1Me Pentaacetate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2,4,7,8,9-Pentaacetyl-D-n-Acetylglycolylneuraminic Acid Methyl Ester is manufactured and analyzed under strict quality management protocols to ensure consistency and high purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.