Description

4-Dimethylaminobut-2-Ynoic Acid Hydrochloride is a versatile chemical intermediate characterized by its unique alkyne and tertiary amine functional groups. This compound is valued for its role in facilitating complex organic synthesis, particularly in the construction of pharmacologically active molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents and advanced material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological and metabolic pathways.
• Organic Synthesis Reagent: Used in click chemistry reactions, Sonogashira couplings, and other palladium-catalyzed cross-coupling processes.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and coordination chemistry.
• Bioconjugation Chemistry: Utilized in the modification of biomolecules (e.g., peptides, proteins) due to its reactive alkyne moiety.
• Material Science Research: Employed in the development of functional polymers and advanced organic materials with tailored properties.
• Agrochemical Synthesis: Acts as an intermediate in the research and development of new crop protection agents.

Basic Information

Product Name	4-Dimethylaminobut-2-Ynoic Acid Hydrochloride
CAS No.	118764-06-0
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	4-(Dimethylamino)but-2-ynoic acid hydrochloride; 2-Butynoic acid, 4-(dimethylamino)-, hydrochloride; 4-Dimethylaminobut-2-ynoic acid HCl; DMABY-HCl; 4-(N,N-Dimethylamino)but-2-ynoic acid hydrochloride; 4-Dimethylamino-2-butynoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Dimethylaminobut-2-Ynoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.