Description

6-Nitrosobenzo(A)Pyrene is a specialized nitroso derivative of the polycyclic aromatic hydrocarbon benzo[a]pyrene, identified by CAS NO 118745-15-6. This compound is of significant interest in advanced chemical research and analytical method development, particularly for studying nitrosation reactions and metabolic pathways of environmental contaminants. It serves as a critical reference standard and synthetic intermediate for researchers and quality control laboratories in the pharmaceutical, environmental monitoring, and toxicology sectors.

Application

• Analytical Reference Standard: Used as a high-purity calibrant and system suitability standard in chromatographic analysis (HPLC, GC-MS) for method validation and quality control.
• Metabolic Pathway Research: Employed in biochemical and toxicological studies to investigate the nitrosation and metabolic activation pathways of polycyclic aromatic hydrocarbons (PAHs).
• Environmental Analysis: Serves as a key analyte in research focused on the detection and quantification of nitro-PAH derivatives in complex environmental matrices like air particulate matter and soil.
• Organic Synthesis Intermediate: Utilized as a building block in the synthesis of more complex molecules for research in medicinal chemistry and material science.
• Toxicological Studies: Applied in *in vitro* and *in vivo* research to assess the mutagenic and carcinogenic potential of nitroso-PAH compounds.

Basic Information

Product Name	6-Nitrosobenzo(A)Pyrene
CAS No.	118745-15-6
Molecular Formula	C₂₀H₁₁NO
Molecular Weight	281.31 g/mol
Synonyms	6-Nitrosobenzo[a]pyrene; Benzo[a]pyrene, 6-nitroso-; 6-Nitroso-BaP; 6-Nitroso-BAP; 6-Nitroso-3,4-Benzpyrene; 6-Nitroso-3,4-Benzopyrene; 6-NBAP
EINECS	Contact for details

Quality Control

Every batch of our 6-Nitrosobenzo(A)Pyrene is manufactured and analyzed under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency for research applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay purity (by HPLC), identity confirmation (by IR/UV), and related substance profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystals
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area Percent)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in common organic solvents (e.g., DMSO, acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.