Description

1-(1,1,1-Trifluoropropan-2-Yl)Hydrazine is a specialized fluorinated hydrazine derivative, a high-value building block prized for introducing the trifluoromethyl group into complex molecular architectures. Its primary commercial value lies in enabling the synthesis of novel compounds with enhanced metabolic stability, lipophilicity, and bioavailability, which are critical properties in modern chemical development. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination to achieve targeted product performance.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with trifluoromethyl motifs, particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials to modify surface properties and dielectric constants.
• Chemical Biology Probes: Useful for incorporating fluorinated tags into biomolecules for study via techniques like 19F NMR spectroscopy.

Basic Information

Product Name	1-(1,1,1-Trifluoropropan-2-Yl)Hydrazine
CAS No.	118737-68-1
Molecular Formula	C3H7F3N2
Molecular Weight	128.10 g/mol
Synonyms	1-(1,1,1-Trifluoropropan-2-yl)hydrazine; 1-(1,1,1-Trifluoro-2-propyl)hydrazine; 2-Hydrazino-1,1,1-trifluoropropane; 1,1,1-Trifluoro-2-propylhydrazine; 1,1,1-Trifluoro-2-hydrazinopropane; (1,1,1-Trifluoropropan-2-yl)hydrazine; TFPH
EINECS	Contact for details

Quality Control

Our 1-(1,1,1-Trifluoropropan-2-Yl)Hydrazine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and specific tests is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.