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(1R,2R)-(+)-N,N'-Dimethyl-1,2-Diphenyl-1,2-Ethane Diamine CAS NO 118628-68-5


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CAS No.:118628-68-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1R,2R)-(+)-N,N'-Dimethyl-1,2-Diphenyl-1,2-Ethane Diamine is a high-purity chiral diamine ligand of significant importance in asymmetric synthesis. This compound matters because it serves as a critical building block and catalyst for creating enantiomerically pure pharmaceuticals and fine chemicals. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and advanced material science, where precise stereochemical control is paramount for product efficacy and performance.

Application

  • Asymmetric Catalysis: A key chiral ligand or catalyst in transition metal-catalyzed reactions such as hydrogenation, hydrosilylation, and conjugate addition.
  • Pharmaceutical Intermediates: Used in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and infections.
  • Agrochemical Synthesis: Employed in the production of chiral pesticides and herbicides to enhance biological activity and reduce environmental impact.
  • Chiral Auxiliary: Functions as a resolving agent or auxiliary in the separation and purification of enantiomers.
  • Material Science Research: A precursor for developing chiral polymers, metal-organic frameworks (MOFs), and other functional materials with specific optical properties.
  • Academic & Industrial R&D: A valuable tool for method development and exploring new asymmetric transformations in chemistry laboratories.

Basic Information

Product Name (1R,2R)-(+)-N,N'-Dimethyl-1,2-Diphenyl-1,2-Ethane Diamine
CAS No. 118628-68-5
Molecular Formula C18H24N2
Molecular Weight 268.40 g/mol
Synonyms (1R,2R)-N,N'-Dimethyl-1,2-diphenylethylenediamine; (R,R)-N,N'-Dimethyl-1,2-diphenylethylenediamine; (1R,2R)-(-)-1,2-Bis[(R)-dimethylamino]ethyl]benzene; (R,R)-DM-DPEN; (R,R)-TMDPEN; (1R,2R)-1,2-Diphenyl-N,N'-dimethylethylenediamine; (R,R)-N,N'-Dimethyl-1,2-diphenyl-1,2-ethanediamine
EINECS Contact for details

Quality Control

Our (1R,2R)-(+)-N,N'-Dimethyl-1,2-Diphenyl-1,2-Ethane Diamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) for each batch, detailing key parameters such as chiral purity, chemical purity, and identity confirmation. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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