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(1R,2R)-(+)-N,N'-Dimethyl-1,2-Diphenyl-1,2-Ethane Diamine CAS NO 118628-68-5
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CAS No.:118628-68-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(1R,2R)-(+)-N,N'-Dimethyl-1,2-Diphenyl-1,2-Ethane Diamine is a high-purity chiral diamine ligand of significant importance in asymmetric synthesis. This compound matters because it serves as a critical building block and catalyst for creating enantiomerically pure pharmaceuticals and fine chemicals. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and advanced material science, where precise stereochemical control is paramount for product efficacy and performance.
Application
- Asymmetric Catalysis: A key chiral ligand or catalyst in transition metal-catalyzed reactions such as hydrogenation, hydrosilylation, and conjugate addition.
- Pharmaceutical Intermediates: Used in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and infections.
- Agrochemical Synthesis: Employed in the production of chiral pesticides and herbicides to enhance biological activity and reduce environmental impact.
- Chiral Auxiliary: Functions as a resolving agent or auxiliary in the separation and purification of enantiomers.
- Material Science Research: A precursor for developing chiral polymers, metal-organic frameworks (MOFs), and other functional materials with specific optical properties.
- Academic & Industrial R&D: A valuable tool for method development and exploring new asymmetric transformations in chemistry laboratories.
Basic Information
| Product Name | (1R,2R)-(+)-N,N'-Dimethyl-1,2-Diphenyl-1,2-Ethane Diamine |
| CAS No. | 118628-68-5 |
| Molecular Formula | C18H24N2 |
| Molecular Weight | 268.40 g/mol |
| Synonyms | (1R,2R)-N,N'-Dimethyl-1,2-diphenylethylenediamine; (R,R)-N,N'-Dimethyl-1,2-diphenylethylenediamine; (1R,2R)-(-)-1,2-Bis[(R)-dimethylamino]ethyl]benzene; (R,R)-DM-DPEN; (R,R)-TMDPEN; (1R,2R)-1,2-Diphenyl-N,N'-dimethylethylenediamine; (R,R)-N,N'-Dimethyl-1,2-diphenyl-1,2-ethanediamine |
| EINECS | Contact for details |
Quality Control
Our (1R,2R)-(+)-N,N'-Dimethyl-1,2-Diphenyl-1,2-Ethane Diamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) for each batch, detailing key parameters such as chiral purity, chemical purity, and identity confirmation. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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