Description

3-Acetoxycholestanol(5,6-B)(n-Phthalimido)Aziridine is a sophisticated, high-purity steroidal aziridine derivative, primarily utilized as a critical synthetic intermediate in advanced organic and medicinal chemistry. Its unique molecular architecture, featuring both a steroidal backbone and a reactive aziridine ring, makes it a valuable building block for constructing complex bioactive molecules. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the development of novel therapeutic agents and for conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel steroidal drugs and potential therapeutic agents targeting various metabolic and hormonal pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for the design, synthesis, and optimization of new chemical entities in drug discovery programs.
• Organic Synthesis Building Block: Employed in advanced organic transformations, leveraging the reactive aziridine moiety for ring-opening reactions to introduce functionalized amine groups into complex molecules.
• Biochemical Probe Development: Acts as a starting material for creating labeled or modified steroidal compounds used in biochemical assays and mechanistic studies.
• Academic & Industrial R&D: A valuable reagent for universities and corporate R&D laboratories focused on steroid chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	3-Acetoxycholestanol(5,6-B)(n-Phthalimido)Aziridine
CAS No.	118517-20-7
Molecular Formula	C37H54N2O4
Molecular Weight	590.85 g/mol
Synonyms	3β-Acetoxy-5α-cholestan-6β-yl N-phthalimidoylaziridine; 3β-Acetoxy-5α-cholestan-6β-yl 1-phthalimidoaziridine; (3β,5α,6β)-3-(Acetyloxy)-cholestan-6-yl 1-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)aziridine; 5,6-B-Aziridino-3β-acetoxycholestane N-phthalimide; Cholestanol, 3-acetate, 5,6-B-(N-phthalimido)aziridine; Aziridine derivative of 3-acetoxycholestanol
EINECS	Contact for details

Quality Control

Our 3-Acetoxycholestanol(5,6-B)(n-Phthalimido)Aziridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and prolonged exposure to air; it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.