Description

7,8,10-Trihydroxy-7,8,9,10-Tetrahydrobenzo(A)Pyrene-9-Sulphonate is a key sulfonated derivative of a polycyclic aromatic hydrocarbon (PAH) metabolite. This compound is of significant interest in biochemical and toxicological research due to its role as a marker for metabolic activation pathways. It is primarily utilized by research institutions and analytical laboratories focused on environmental monitoring, carcinogenicity studies, and the development of detection methods for PAH exposure.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in studies investigating the metabolic pathways and detoxification of Benzo(a)pyrene and related PAHs.
• Toxicology & Carcinogenicity Studies: Serves as a critical analyte in research aimed at understanding the mechanisms of PAH-induced toxicity and cancer development.
• Environmental Analysis: Employed in the development and validation of analytical methods (e.g., HPLC, LC-MS) for detecting and quantifying PAH metabolites in environmental and biological samples.
• Diagnostic Assay Development: Acts as a calibrant or control in the creation of immunoassays or other diagnostic tests designed to measure human exposure to carcinogenic PAHs.
• Pharmaceutical Intermediates: Potential use as a specialized synthetic intermediate in the research and development of novel therapeutic agents or molecular probes.

Basic Information

Product Name	7,8,10-Trihydroxy-7,8,9,10-Tetrahydrobenzo(A)Pyrene-9-Sulphonate
CAS No.	118499-61-9
Molecular Formula	C₂₀H₁₄O₇S
Molecular Weight	398.38 g/mol
Synonyms	Benzo[a]pyrene-7,8,10-triol-9-sulfonate; 7,8,10-Trihydroxy-7,8,9,10-tetrahydrobenzo[a]pyren-9-yl hydrogen sulfate; 9-Sulfooxy-7,8,10-trihydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene; BPDE-9-sulfate; Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide sulfate ester; (+)-anti-BPDE-9-sulfate; BaP-7,8,10-triol-9-SO₃H
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results from HPLC, NMR, and MS are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material at -20°C under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.