Description

2-(4-Chlorobutyl)-1,3-Dioxolane is a versatile chlorinated acetal building block of significant interest in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a reactive chloroalkyl chain and a protected aldehyde moiety, enabling its use in the construction of complex molecular frameworks. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring a functionalized butyl chain.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the chlorobutyl-dioxolane unit is incorporated.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with unique properties.
• Ligand & Catalyst Development: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing specific aroma chemicals and flavor compounds.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution, cyclization, and deprotection reactions to introduce functional groups.

Basic Information

Product Name	2-(4-Chlorobutyl)-1,3-Dioxolane
CAS No.	118336-86-0
Molecular Formula	C7H13ClO2
Molecular Weight	164.63 g/mol
Synonyms	4-Chlorobutyl Acetaldehyde Ethylene Acetal; 1,3-Dioxolane, 2-(4-chlorobutyl)-; 4-Chloro-1-butanal Ethylene Acetal; (4-Chlorobutyl)acetaldehyde Ethylene Acetal; 2-(4-Chlorobutyl)-1,3-dioxacyclopentane; 4-Chlorobutanal Ethylene Acetal; Acetaldehyde, (4-chlorobutyl)-, cyclic acetal with ethylene glycol
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorobutyl)-1,3-Dioxolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.455
Density (g/mL, 20°C)	1.10 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.