Description

(2S)-(+)-2-Methylglycidyl 4-Nitrobenzoate is a high-purity chiral epoxide derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry and reactive epoxide ring make it invaluable for introducing specific molecular frameworks with high enantiomeric purity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and catalysts used in asymmetric catalysis.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and stereoselective synthesis research.
• Polymer Modification: Can be used to introduce chiral epoxy functionalities into polymer backbones for advanced material properties.

Basic Information

Product Name	(2S)-(+)-2-Methylglycidyl 4-Nitrobenzoate
CAS No.	118200-96-7
Molecular Formula	C11H11NO5
Molecular Weight	237.21 g/mol
Synonyms	(2S)-(-)-2-Methyloxiranylmethyl 4-nitrobenzoate; (S)-(-)-2-Methylglycidyl 4-Nitrobenzoate; 4-Nitrobenzoic Acid (2S)-(-)-2-Methyloxiranylmethyl Ester; (S)-Methylglycidyl 4-Nitrobenzoate; (2S)-2-Methylglycidyl p-Nitrobenzoate; (-)-2-Methylglycidyl 4-Nitrobenzoate; (S)-(-)-2-Methylglycidyl p-Nitrobenzoate
EINECS	Contact for details

Quality Control

Our (2S)-(+)-2-Methylglycidyl 4-Nitrobenzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.