Description

Fmoc-Nh(Ch2)5Nh2 Hcl is a protected diamine building block, specifically an Fmoc-protected 1,5-diaminopentane hydrochloride salt, with CAS number 118119-32-7. This compound is essential for the controlled, sequential synthesis of peptides and peptidomimetics in solid-phase peptide synthesis (SPPS). It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for introducing a diaminoalkyl linker or spacer within peptide chains.
• Peptidomimetic Drug Discovery: Used to create structurally modified peptide analogs with enhanced stability or biological activity.
• Bioconjugation and Linker Chemistry: Serves as a versatile precursor for synthesizing heterobifunctional crosslinking agents.
• Dendrimer and Polymer Synthesis: Acts as a functional monomer for constructing branched macromolecular architectures.
• Combinatorial Chemistry Libraries: A valuable reagent for generating diverse compound libraries for high-throughput screening.
• Surface Functionalization: Used to modify surfaces with amine groups for subsequent biomolecule immobilization.

Basic Information

Product Name	Fmoc-Nh(Ch2)5Nh2 Hcl
CAS No.	118119-32-7
Molecular Formula	C₂₁H₂₇N₂O₂•HCl
Molecular Weight	384.91 g/mol
Synonyms	Fmoc-1,5-diaminopentane hydrochloride; Nα-Fmoc-1,5-diaminopentane hydrochloride; N-(9-Fluorenylmethoxycarbonyl)-1,5-diaminopentane hydrochloride; Fmoc-DAP(HCl); Fmoc-Lys(NH2)-OH hydrochloride (deprotected side chain); 5-[(9H-Fluoren-9-ylmethoxy)carbonylamino]pentylamine hydrochloride
EINECS	Contact for details

Quality Control

Our Fmoc-Nh(Ch2)5Nh2 Hcl is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.