Description

Sialyl-Le(A) Oligosaccharide CAS NO 117978-16-2 is a complex, biologically significant carbohydrate structure featuring sialic acid and Lewis A antigen motifs. This compound is a critical research tool and a high-value intermediate for investigating cell-cell recognition, inflammation, and cancer metastasis. It is primarily utilized by researchers and developers in the pharmaceutical, diagnostic, and biotechnology sectors for glycan array construction, biomarker discovery, and the development of therapeutic antibodies or inhibitors.

Application

• Glycobiology Research: A key standard and probe for studying carbohydrate-protein interactions, particularly with selectins and siglecs.
• Diagnostic Development: Used in the design and calibration of immunoassays and biosensors for detecting cancer-associated antigens or inflammatory markers.
• Vaccine & Therapeutic Discovery: Serves as a target epitope or hapten in the development of anti-cancer vaccines and carbohydrate-based therapeutic agents.
• Biomarker Analysis: Employed as a reference compound in mass spectrometry and HPLC-based profiling of glycan biomarkers in biological fluids.
• Enzyme Substrate: Acts as a specific substrate for studying the activity of glycosyltransferases, sialidases, and other glycan-modifying enzymes.
• Cell Culture & Adhesion Studies: Used to modulate or inhibit cell adhesion processes in immunological and cancer research models.

Basic Information

Product Name	Sialyl-Le(A) Oligosaccharide
CAS No.	117978-16-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sialyl Lewis A; Sialyl Lea; CA19-9 Antigen; Sialylated Lewis A; Neu5Acα2-3Galβ1-3[Fucα1-4]GlcNAc; Monosialyl Lewis A; 3'-Sialyl-N-acetyllactosamine Lewis a; SLea
EINECS	Contact for details

Quality Control

Our Sialyl-Le(A) Oligosaccharide is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, MS and NMR for structural confirmation, and specific optical rotation analysis. Certificates of Analysis (COA) detailing all test results are provided to ensure full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Biological Activity (Binding Assay)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.