Description

2-Acetamido-1,5-Imino-1,2,5-Trideoxy-D-Galactitol is a specialized chiral iminosugar derivative with a galactitol backbone, serving as a high-value building block and research chemical. This compound is critical for its role as a potent and selective glycosidase inhibitor, enabling advanced biochemical and pharmacological research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on developing novel therapeutics, enzyme probes, and carbohydrate-based diagnostics.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel glycosidase inhibitor drugs targeting conditions like diabetes, viral infections (e.g., influenza, HIV), and lysosomal storage disorders.
• Biochemical Research: Essential tool compound for studying enzyme mechanisms, specifically for probing the active sites and inhibition kinetics of α- and β-galactosidases and other related enzymes.
• Glycobiology & Glycomics: Used in the synthesis of complex oligosaccharide mimics and glycan arrays to investigate carbohydrate-protein interactions critical in cell signaling and immunology.
• Agrochemical Research: Investigated for the development of next-generation plant growth regulators or pest control agents that target insect or fungal carbohydrate metabolism.
• Diagnostic Reagent Development: Serves as a precursor for manufacturing enzyme substrates or inhibitors used in clinical diagnostic kits for metabolic enzyme activity assays.

Basic Information

Product Name	2-Acetamido-1,5-Imino-1,2,5-Trideoxy-D-Galactitol
CAS No.	117894-14-1
Molecular Formula	C8H16N2O5
Molecular Weight	220.22 g/mol
Synonyms	1,5-Dideoxy-1,5-imino-2-acetamido-D-galactitol; 2-Acetamido-1,5-dideoxy-1,5-imino-D-galactitol; D-Galactitol, 2-acetamido-1,5-imino-1,2,5-trideoxy-; 2-Acetamido-1,5-imino-1,2,5-trideoxygalactitol; 2-Acetamido-1,5-iminogalactitol; Galactostatin B derivative; Iminosugar derivative; Glycosidase inhibitor intermediate
EINECS	Contact for details

Quality Control

Every batch of 2-Acetamido-1,5-Imino-1,2,5-Trideoxy-D-Galactitol is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay purity, chiral purity, and impurity profiles. Our quality commitment supports compliance with relevant guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.