Description

Fmoc-Bpa-Oh CAS NO 117666-96-3 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block for the controlled incorporation of the photoreactive amino acid p-benzoylphenylalanine (Bpa) into peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of photoaffinity labeling probes, peptide-based therapeutics, and advanced biomaterials.

Application

• Photoaffinity Labeling Probe Synthesis: Key reagent for introducing the benzophenone moiety of Bpa into peptides to study protein-protein interactions and ligand binding sites.
• Peptide-Based Drug Discovery: Used in SPPS to create peptide analogs with cross-linking capabilities for therapeutic and diagnostic applications.
• Bioconjugation and Biomaterial Development: Enables the site-specific modification of peptides for conjugation to other molecules, surfaces, or polymers.
• Structural Biology Research: Facilitates the production of peptides for cross-linking experiments in mass spectrometry and structural analysis.
• Chemical Biology Tool Development: Employed in creating molecular tools to probe enzyme mechanisms and cellular pathways.

Basic Information

Product Name	Fmoc-Bpa-Oh
CAS No.	117666-96-3
Molecular Formula	C31H25NO5
Molecular Weight	491.54 g/mol
Synonyms	Fmoc-p-benzoyl-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-benzoyl-L-phenylalanine; Fmoc-4-benzoyl-L-phenylalanine; Fmoc-Bpa-OH; Fmoc-L-4-benzoylphenylalanine; N-α-Fmoc-4-benzoyl-L-phenylalanine; (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[4-(phenylcarbonyl)phenyl]propanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Bpa-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for peptide synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment. We support cGMP-compliant production for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.