Description

1-Bromo-3,3-Dimethyl-Butan-2-Ol is a versatile brominated tertiary alcohol building block used in advanced organic synthesis. This compound is valued for its ability to introduce the bulky 3,3-dimethyl-2-hydroxybutyl moiety, which is crucial for modifying molecular properties in target compounds. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from active pharmaceutical ingredient (API) intermediates to performance material precursors.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of complex molecules, potentially serving as a precursor for active pharmaceutical ingredients (APIs) or prodrugs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators where the tertiary alcohol and bromine functionalities are leveraged.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands or organocatalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce functional groups into polymer chains to alter physical properties like solubility, glass transition temperature, or reactivity.
• Fine Chemical Production: Serves as a building block for various high-value specialty chemicals, including flavors, fragrances, and advanced material monomers.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry, including new coupling reactions and functional group transformations.

Basic Information

Product Name	1-Bromo-3,3-Dimethyl-Butan-2-Ol
CAS No.	117658-14-7
Molecular Formula	C6H13BrO
Molecular Weight	181.07 g/mol
Synonyms	2-Bromo-3,3-dimethylbutan-2-ol; 3,3-Dimethyl-2-bromo-2-butanol; 2-Butanol, 2-bromo-3,3-dimethyl-; Pinacolyl Bromohydrin; 1-Bromo-3,3-dimethylbutan-2-ol; tert-Butyl bromomethyl carbinol
EINECS	Contact for details

Quality Control

Our 1-Bromo-3,3-Dimethyl-Butan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by GC/HPLC), identity confirmation (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.