Description

4(1H)-Quinazolinone, 2-(Bromomethyl)-5,8-Dihydroxy- (9Ci) is a functionalized quinazolinone derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and dihydroxy substituents, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents with optimized properties.
• Organic Synthesis Building Block: The reactive bromomethyl group allows for further functionalization, making it valuable for creating custom-designed molecular libraries.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Bioconjugation & Probe Development: Potential use in creating fluorescent probes or affinity labels for biochemical and diagnostic applications.

Basic Information

Item	Detail
Product Name	4(1H)-Quinazolinone, 2-(Bromomethyl)-5,8-Dihydroxy- (9Ci)
CAS No.	117498-05-2
Molecular Formula	C9H7BrN2O3
Molecular Weight	271.07 g/mol
Synonyms	2-(Bromomethyl)-5,8-dihydroxy-4(1H)-quinazolinone; 5,8-Dihydroxy-2-(bromomethyl)-4(1H)-quinazolinone; 2-Bromomethyl-5,8-dihydroxy-1H-quinazolin-4-one; 117498-05-2; Quinazolinone, 2-(bromomethyl)-5,8-dihydroxy-4(1H)- (9CI)
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinazolinone, 2-(Bromomethyl)-5,8-Dihydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.