Description

Spiro[Bicyclo[3.1.0]Hexane-6,2-[1,3]Dioxolane], 2-Methyl-, [1R-(1-α-,2-α-,5-α-)]- (9Ci) is a high-purity, stereochemically defined spirocyclic compound. This molecule serves as a critical chiral building block and advanced intermediate in the synthesis of complex organic molecules. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis: Utilized as a sophisticated ligand or precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Agrochemical Research: Serves as a building block for creating novel, stereospecific active ingredients for crop protection products.
• Material Science: Potential monomer or precursor for synthesizing specialty polymers with unique structural properties.
• Academic & Industrial R&D: Used in methodological chemistry research and process development for complex molecule construction.
• Flavor & Fragrance Industry: Intermediate for the synthesis of stereochemically pure aroma chemicals.

Basic Information

Product Name	Spiro[Bicyclo[3.1.0]Hexane-6,2-[1,3]Dioxolane], 2-Methyl-, [1R-(1-α-,2-α-,5-α-)]- (9Ci)
CAS No.	117465-67-5
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1R,2R,5R)-2-Methylspiro[bicyclo[3.1.0]hexane-6,2'-[1,3]dioxolane]; [1R-(1α,2α,5α)]-2-Methylspiro[bicyclo[3.1.0]hexane-6,2'-[1,3]dioxolane]; 2-Methylspiro[bicyclo[3.1.0]hexane-6,2'-[1,3]dioxolane], (1R,2R,5R)-rel-; Spiro[bicyclo[3.1.0]hexane-6,2'-[1,3]dioxolane], 2-methyl-, (1R,2R,5R)-; (1R,2R,5R)-2-Methyl-6,2-epoxy-1,3-dioxolane-spiro-bicyclo[3.1.0]hexane
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, chiral analysis, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.