Description

Spiro[Bicyclo[3.1.0]Hexane-6,2-[1,3]Dioxolane], 2-Methyl-, [1R-(1-α-,2-β-,5-α-)]- (9Ci) is a high-purity, stereochemically defined spirocyclic compound used as a critical chiral building block in advanced organic synthesis. Its unique fused bicyclic and dioxolane structure makes it a valuable intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Spiro[Bicyclo[3.1.0]Hexane-6,2-[1,3]Dioxolane], 2-Methyl-, [1R-(1-α-,2-β-,5-α-)]- (9Ci)
CAS No.	117465-62-0
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1R,2S,5R)-2-Methylspiro[bicyclo[3.1.0]hexane-6,2'-[1,3]dioxolane]; [1R-(1α,2β,5α)]-2-Methylspiro[bicyclo[3.1.0]hexane-6,2'-[1,3]dioxolane]; 2-Methylspiro[bicyclo[3.1.0]hexane-6,2'-[1,3]dioxolane], (1R,2S,5R)-rel-; Spiro[bicyclo[3.1.0]hexane-6,2'-[1,3]dioxolane], 2-methyl-, (1R,2S,5R)-; (1R,2S,5R)-2-Methyl-6,2-epoxy-1,3-dioxolane-bicyclo[3.1.0]hexane
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[3.1.0]Hexane-6,2-[1,3]Dioxolane], 2-Methyl-, [1R-(1-α-,2-β-,5-α-)]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.