Description

3-Iodo-4-Phenyl-1,2-Dihydro-Naphthalene is a high-purity, functionalized naphthalene derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a phenyl group on a partially saturated naphthalene core, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and oncological diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure for bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Organic Synthesis Building Block: Employed in cyclization and annulation reactions to construct polycyclic aromatic hydrocarbons (PAHs) and other complex fused-ring systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Item	Detail
Product Name	3-Iodo-4-Phenyl-1,2-Dihydro-Naphthalene
CAS No.	117408-90-9
Molecular Formula	C₁₆H₁₃I
Molecular Weight	332.18 g/mol
Synonyms	1,2-Dihydro-3-iodo-4-phenylnaphthalene; 4-Phenyl-3-iodo-1,2-dihydronaphthalene; 3-Iodo-4-phenyl-1,2-dihydronaphthalene; NSC 405124; 1,2-Dihydronaphthalene, 3-iodo-4-phenyl-; 3-Iodo-4-phenyl-1,2-dihydro-naphthalene; 4-Phenyl-3-iodo-1,2-dihydronaphthalene
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Phenyl-1,2-Dihydro-Naphthalene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.