Description

3-(2-Bromophenyl)-3-[(2,2,2-Trifluoroacetyl)Amino]Propanoic Acid is a specialized brominated and trifluoroacetylated amino acid derivative, serving as a high-value synthetic intermediate. Its core value proposition lies in its unique molecular architecture, which provides a versatile scaffold for constructing complex molecules in advanced pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the development of protease inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for targeted therapies and enzyme inhibitors.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors due to its specific bromophenyl and trifluoroacetyl amino acid structure.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced, high-performance crop protection agents with unique modes of action.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in activity-based protein profiling (ABPP) and other biochemical studies.
• Peptidomimetic Development: Acts as a non-natural amino acid analog for designing and synthesizing stable peptide mimics with enhanced pharmacological properties.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with specific optical or electronic characteristics.

Basic Information

Product Name	3-(2-Bromophenyl)-3-[(2,2,2-Trifluoroacetyl)Amino]Propanoic Acid
CAS No.	117291-11-9
Molecular Formula	C11H9BrF3NO3
Molecular Weight	340.10 g/mol
Synonyms	3-[(2,2,2-Trifluoroacetyl)amino]-3-(2-bromophenyl)propanoic acid; 3-Amino-3-(2-bromophenyl)propanoic acid N-trifluoroacetyl; 2-Bromophenylalanine N-trifluoroacetyl derivative; N-(Trifluoroacetyl)-3-(2-bromophenyl)-β-alanine; 3-(2-Bromophenyl)-3-(2,2,2-trifluoroacetamido)propionic acid; β-(2-Bromophenyl)-N-trifluoroacetyl-β-alanine; (R/S)-3-(2-Bromophenyl)-3-[(2,2,2-trifluoroacetyl)amino]propanoic acid
EINECS	Contact for details

Quality Control

Our 3-(2-Bromophenyl)-3-[(2,2,2-Trifluoroacetyl)Amino]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and precise determination of residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled in a manner that minimizes exposure to strong acids and organic solvents. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.