Description

(R)-4-Amino-2-Hydroxybutanoic Acid Hydrochloride is a high-purity chiral building block and intermediate of significant importance in pharmaceutical research and development. This compound is valued for its role in the synthesis of active pharmaceutical ingredients (APIs) and novel therapeutic agents, particularly those targeting neurological and metabolic pathways. It is primarily needed by R&D laboratories, process chemists, and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of γ-aminobutyric acid (GABA) analogs and other neuroactive compounds.
• API Synthesis: Used in the research and production of Active Pharmaceutical Ingredients (APIs) requiring a specific (R)-enantiomer configuration.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme inhibition research.
• Peptide Modification: Employed in the design and synthesis of modified peptides and peptidomimetics to alter biological activity.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in catalytic asymmetric synthesis for creating complex chiral molecules.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R)-4-Amino-2-Hydroxybutanoic Acid Hydrochloride
CAS No.	117173-81-6
Molecular Formula	C₄H₁₀ClNO₃
Molecular Weight	155.58 g/mol
Synonyms	(R)-4-Amino-2-hydroxybutyric acid hydrochloride; (R)-2-Hydroxy-4-aminobutyric acid hydrochloride; (R)-HABA hydrochloride; (R)-γ-Amino-β-hydroxybutyric acid hydrochloride; (R)-4-Amino-2-hydroxy-butanoic acid hydrochloride; (R)-GABOB hydrochloride; (R)-3-Amino-2-hydroxypropylacetic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-4-Amino-2-Hydroxybutanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.