Description

1,11-Ditosyl-1,4,8,11-Tetraazacyclotetradecane Dihydrochloride is a high-purity, functionalized macrocyclic ligand derivative, specifically a tosylated cyclam compound. This chemical is a critical intermediate and building block for the synthesis of sophisticated metal chelators and radiopharmaceutical precursors. It is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and advanced materials sectors who require precise molecular scaffolds for developing targeted therapies and imaging agents.

Application

• Radiopharmaceutical Precursor: Serves as a key intermediate for synthesizing chelating agents used in positron emission tomography (PET) and single-photon emission computed tomography (SPECT) imaging.
• Metal Chelator Synthesis: Used to create functionalized cyclam derivatives for binding transition metals and lanthanides in catalysis and material science.
• Pharmaceutical Intermediate: Acts as a building block in the development of novel therapeutic agents, including anticancer and antiviral compounds.
• Diagnostic Agent Development: Employed in the research and production of contrast agents for magnetic resonance imaging (MRI).
• Coordination Chemistry Research: A valuable reagent for academic and industrial research into macrocyclic chemistry and supramolecular assemblies.
• Sensor Technology: Used in the development of chemical sensors and probes due to its selective metal-binding properties.

Basic Information

Product Name	1,11-Ditosyl-1,4,8,11-Tetraazacyclotetradecane Dihydrochloride
CAS No.	117152-73-5
Molecular Formula	C30H50Cl2N4O4S2
Molecular Weight	657.8 g/mol
Synonyms	1,11-Bis(p-toluenesulfonyl)-1,4,8,11-tetraazacyclotetradecane dihydrochloride; 1,11-Di-p-toluenesulfonyl-1,4,8,11-tetraazacyclotetradecane dihydrochloride; Ditosyl cyclam dihydrochloride; Ts2Cyclam·2HCl; 1,4,8,11-Tetraazacyclotetradecane-1,11-ditosylate dihydrochloride; 1,11-Di(tosyl)-1,4,8,11-tetraazacyclotetradecane dihydrochloride
EINECS	Contact for details

Quality Control

Our 1,11-Ditosyl-1,4,8,11-Tetraazacyclotetradecane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed specifications from methods including HPLC, NMR, and elemental analysis are provided to guarantee traceability and compliance with your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.