Description

Oxiranecarboxylic Acid, 3-(Hydroxymethyl)-, Ethyl Ester, (2R-Trans)- (9Ci) is a high-purity chiral glycidol derivative, serving as a critical building block in asymmetric synthesis. Its value lies in providing a stereochemically defined, reactive epoxide moiety for the controlled introduction of functional groups. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-blockers, antiviral agents, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or cross-linking agent for creating advanced polymers with specific optical or mechanical properties.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in the development and testing of new chiral catalysts.
• Fine Chemical Production: Utilized for the manufacture of specialty chemicals, flavors, and fragrances where stereochemical purity is paramount.
• Bioconjugation & Probe Development: The reactive epoxide group enables selective labeling and modification of biomolecules for diagnostic and research applications.

Basic Information

Item	Detail
Product Name	Oxiranecarboxylic Acid, 3-(Hydroxymethyl)-, Ethyl Ester, (2R-Trans)- (9Ci)
CAS No.	117069-18-8
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	(2R,3S)-3-(Hydroxymethyl)oxirane-2-carboxylic acid ethyl ester; Ethyl (2R,3S)-3-(hydroxymethyl)oxirane-2-carboxylate; (-)-(2R,3S)-Ethyl 3-(hydroxymethyl)glycidate; (2R,3S)-Ethyl 3-(hydroxymethyl)oxiranecarboxylate; (2R,3S)-Ethyl glycidate 3-carbinol; Chiral glycidol ester; (R)-(-)-Ethyl 3-hydroxy-2-oxiranecarboxylate; trans-Ethyl 3-(hydroxymethyl)glycidate
EINECS	Contact for details

Quality Control

Every batch of Oxiranecarboxylic Acid, 3-(Hydroxymethyl)-, Ethyl Ester, (2R-Trans)- (9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles verified by techniques such as HPLC, GC, and chiral analysis. Our quality commitment ensures material suitable for GMP-grade pharmaceutical synthesis and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.