Description

2,3-Dihydro-3-(2-Methylprop-1-Yl)-2-Thioxoquinazolin-4(1H)-One, 3-Isobutyl-4-Oxo-1,2,3,4-Tetrahydro-2-Thioxoquinazoline is a specialized heterocyclic organic compound belonging to the quinazolinone class, distinguished by its thioxo and isobutyl substituents. This compound serves as a critical synthetic intermediate and a versatile scaffold in advanced organic chemistry, enabling the development of novel molecular structures with targeted properties. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and academic research institutions engaged in developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in the development of kinase inhibitors, antimicrobials, and central nervous system (CNS) agents.
• Agrochemical Research: Used as a precursor in the synthesis of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis Scaffold: Serves as a versatile starting material for constructing complex heterocyclic libraries for high-throughput screening (HTS) in drug discovery.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers and organic electronic materials due to its conjugated system.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies in organic synthesis and medicinal chemistry.
• Dye & Pigment Intermediate: Explored for the synthesis of novel heterocyclic dyes and colorants, given the chromophoric nature of the quinazolinone structure.

Basic Information

Product Name	2,3-Dihydro-3-(2-Methylprop-1-Yl)-2-Thioxoquinazolin-4(1H)-One, 3-Isobutyl-4-Oxo-1,2,3,4-Tetrahydro-2-Thioxoquinazoline
CAS No.	117038-39-8
Molecular Formula	C₁₃H₁₆N₂OS
Molecular Weight	248.34 g/mol
Synonyms	3-Isobutyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one; 3-Isobutyl-4-oxo-1,2,3,4-tetrahydro-2-thioxoquinazoline; 3-(2-Methylpropyl)-2-sulfanylidene-1H-quinazolin-4-one; 3-Isobutyl-2-thio-4-quinazolinone; 3-Isobutyl-2-thioxo-1,2,3,4-tetrahydro-4-quinazolinone; Quinazoline-4(1H)-one, 2,3-dihydro-3-(2-methylpropyl)-2-thioxo-; 3-Isobutyl-2-thioxoquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our production of 2,3-Dihydro-3-(2-Methylprop-1-Yl)-2-Thioxoquinazolin-4(1H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all specifications. We support cGMP and ISO 9001 compliant manufacturing for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.