Description

2-Oxo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular therapeutic areas. It is essential for research institutions and pharmaceutical manufacturers engaged in the development and production of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially those targeting neurological pathways.
• API Synthesis: Serves as a core scaffold for the development of new benzazepine-based active pharmaceutical ingredients.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	2-Oxo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine-7-Carboxylic Acid
CAS No.	117030-69-0
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	7-Carboxy-2,3,4,5-tetrahydro-1H-2-benzazepin-1-one; 1H-2-Benzazepine-7-carboxylic acid, 2,3,4,5-tetrahydro-1-oxo-; 2,3,4,5-Tetrahydro-1-oxo-1H-2-benzazepine-7-carboxylic acid; 2-Oxo-2,3,4,5-tetrahydrobenzo[b]azepine-7-carboxylic acid; Benzo[b]azepine-7-carboxylic acid derivative; 117030-69-0; Tetrahydrobenzazepinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine-7-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.