Description

Posiphen is a small molecule compound of significant interest in pharmaceutical research and development. Its primary value lies in its potential as a neuroprotective agent and its role in modulating key biological pathways. This makes it a critical material for researchers and manufacturers in the life sciences sector, particularly those focused on neurodegenerative diseases and central nervous system disorders. The compound is supplied to meet the stringent requirements of preclinical and clinical-stage pharmaceutical applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced investigational drugs.
• Neurological Research: Used in in vitro and in vivo studies targeting Alzheimer's disease and related dementias.
• Mechanism of Action Studies: Employed to investigate the modulation of amyloid precursor protein (APP) metabolism.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in laboratories.
• Preclinical Development: Utilized in formulation studies and pharmacokinetic/pharmacodynamic (PK/PD) modelling for candidate drugs.

Basic Information

Product Name	Posiphen
CAS No.	116839-68-0
Molecular Formula	C₁₇H₂₁N₃O₂
Molecular Weight	299.37 g/mol
Synonyms	(-)-Phenserine; (3aS,8aR)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl methylcarbamate; Posiphen tartrate (salt form); UNII-6Q5M117B7P
EINECS	Contact for details

Quality Control

Our Posiphen is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements for preclinical and clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.