Description

3-(2-Fluorophenoxy)Propan-1-Amine Hydrochloride is a high-purity organic intermediate featuring a fluorinated aromatic ether linked to a primary amine hydrochloride salt. This compound is valued for its role as a critical building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and insecticides where the fluorophenoxy moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Life Science Research: Employed in biochemical research as a tool compound for studying enzyme inhibition and receptor binding.
• Material Science: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-(2-Fluorophenoxy)Propan-1-Amine Hydrochloride
CAS No.	116735-67-2
Molecular Formula	C9H12FNO•HCl
Molecular Weight	203.66 g/mol (Free base: 167.20 g/mol)
Synonyms	1-Amino-3-(2-fluorophenoxy)propane hydrochloride; 3-(2-Fluorophenoxy)propylamine hydrochloride; 2-Fluorophenoxypropylamine HCl; 1-Propanamine, 3-(2-fluorophenoxy)-, hydrochloride; γ-(2-Fluorophenoxy)propylamine hydrochloride; 3-(2-Fluorophenoxy)-1-propanamine hydrochloride; 2-Fluorophenoxypropan-1-amine HCl
EINECS	Contact for details

Quality Control

Our 3-(2-Fluorophenoxy)Propan-1-Amine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed and under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH limits
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.