Description

3-Bromo-5-Nitrophenol is a halogenated nitrophenol derivative, a versatile and high-purity organic intermediate essential for advanced chemical synthesis. Its unique structure, featuring both bromo and nitro functional groups, makes it a critical building block for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty dyes, and advanced material science applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and colorants for high-performance applications.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Research & Development: A valuable reagent for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Laboratory Reagent: Used as a standard or starting material in analytical and synthetic chemistry laboratories.

Basic Information

Product Name	3-Bromo-5-Nitrophenol
CAS No.	116632-23-6
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	5-Nitro-3-bromophenol; 3-Bromo-5-nitrophenol; Phenol, 3-bromo-5-nitro-; 3-Brom-5-nitrophenol; 3-Bromo-5-hydroxy-nitrobenzene; 2-Bromo-6-nitrophenol (tautomer); NSC 403779; 116632-23-6
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Nitrophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.