Description

Methyl 3-Amino-1-Cyano-4-Fluoro-1-(4-Fluorophenyl)-1H-Indene-2-Carboxylate is a high-purity, multi-functional indene derivative that serves as a critical advanced intermediate in modern synthetic chemistry. This compound is valued for its unique molecular scaffold, which incorporates amino, cyano, and fluoro substituents, enabling precise structural modifications and the synthesis of complex target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic frameworks.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atoms and indene core can contribute to biological activity and metabolic stability.
• Material Science Precursor: Serves as a specialized monomer or precursor for advanced polymers and functional materials with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions involving its amino and cyano functional groups.
• Fluorine Chemistry Studies: Acts as a model compound in research focused on the synthesis and reactivity of fluorinated aromatic systems.

Basic Information

Product Name	Methyl 3-Amino-1-Cyano-4-Fluoro-1-(4-Fluorophenyl)-1H-Indene-2-Carboxylate
CAS No.	116616-96-7
Molecular Formula	C18H12F2N2O2
Molecular Weight	326.30 g/mol
Synonyms	Methyl 3-amino-1-cyano-4-fluoro-1-(4-fluorophenyl)-1H-indene-2-carboxylate; 1H-Indene-2-carboxylic acid, 3-amino-1-cyano-4-fluoro-1-(4-fluorophenyl)-, methyl ester; 3-Amino-1-cyano-4-fluoro-1-(4-fluorophenyl)-1H-indene-2-carboxylic acid methyl ester; 116616-96-7; Methyl 3-amino-1-cyano-4-fluoro-1-(p-fluorophenyl)indene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-1-Cyano-4-Fluoro-1-(4-Fluorophenyl)-1H-Indene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.