Description

2-(1H-Tetrazol-1-yl)benzoic acid is a specialized heterocyclic compound that combines a benzoic acid scaffold with a tetrazole moiety, creating a versatile building block for advanced synthesis. This unique structure is critical for applications requiring specific molecular recognition or the modulation of physicochemical properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for use as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting cardiovascular and central nervous system diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators where the tetrazole ring acts as a bioisostere.
• Coordination Chemistry & Material Science: Serves as a ligand for metal-organic frameworks (MOFs) and catalysts due to its carboxylic acid and nitrogen-rich tetrazole functional groups.
• Peptide Mimetics & Drug Design: The tetrazole ring is employed as a metabolically stable surrogate for a carboxylic acid or cis-amide bond in medicinal chemistry.
• Chemical Synthesis Building Block: Utilized in organic synthesis for cycloaddition reactions and to introduce specific steric and electronic properties into target molecules.

Basic Information

Product Name	2-(1H-Tetrazol-1-yl)benzoic Acid
CAS No.	116570-12-8
Molecular Formula	C8H6N4O2
Molecular Weight	190.16 g/mol
Synonyms	1H-Tetrazole-1-benzoic acid, 2-(1H-Tetrazol-1-yl)benzoic acid; 2-(Tetrazol-1-yl)benzoic acid; Benzoic acid, 2-(1H-tetrazol-1-yl)-; 1-(2-Carboxyphenyl)-1H-tetrazole; o-(1H-Tetrazol-1-yl)benzoic acid; 2-(1H-1,2,3,4-Tetrazol-1-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-(1H-Tetrazol-1-yl)benzoic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.