Description

Fructose 2-Phosphorothioate 6-Phosphate is a specialized biochemical reagent featuring a phosphorothioate modification, which confers unique stability and reactivity compared to its phosphate counterparts. This compound is critical for research in enzymology and metabolic pathway analysis, particularly in studies involving carbohydrate metabolism and kinase/phosphatase activity. It serves as a valuable tool for pharmaceutical researchers, diagnostic kit developers, and academic biochemists investigating cellular energy regulation and signal transduction mechanisms.

Application

• Enzymology Research: Used as a substrate or inhibitor in kinetic studies of carbohydrate-metabolizing enzymes like kinases and phosphatases.
• Metabolic Pathway Analysis: A key intermediate for probing and modulating specific steps in glycolysis, gluconeogenesis, and other sugar phosphate pathways.
• Pharmaceutical Development: Employed in high-throughput screening assays to identify novel therapeutic agents targeting metabolic disorders or infectious diseases.
• Diagnostic Reagent Manufacturing: Serves as a critical raw material in the formulation of enzymatic assay kits for clinical and research laboratories.
• Biochemical Tool Compound: Provides a hydrolysis-resistant analog for tracing phosphate group transfer and studying enzyme mechanism of action.
• Academic & Institutional Research: Essential for fundamental studies in biochemistry, molecular biology, and chemical biology related to energy metabolism.

Basic Information

Product Name	Fructose 2-Phosphorothioate 6-Phosphate
CAS No.	116482-98-5
Molecular Formula	C6H14O12P2S
Molecular Weight	380.17 g/mol
Synonyms	Fructose-2,6-bisphosphorothioate; 2-Thio-Fructose-2,6-bisphosphate; Fructose 2,6-Bisphosphorothioic Acid; Fru-2,6-PS2; 6-O-Phosphono-2-thio-D-fructofuranose 2-phosphate; D-Fructose 2,6-bis(phosphorothioate); F2,6BP(S)2; Fructose-2,6-bisphosphorothioate sodium salt (common salt form)
EINECS	Contact for details

Quality Control

Our Fructose 2-Phosphorothioate 6-Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to prevent condensation and hydrolysis. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.