Description

2,3-Methanopyroglutamic Acid is a specialized heterocyclic compound featuring a constrained bicyclic structure. This unique molecular architecture makes it a valuable synthetic intermediate and building block in advanced organic synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals and bioactive compounds. The compound is supplied with a high level of purity to meet the stringent requirements of modern chemical research and development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic pathways.
• Peptidomimetics Research: Used to introduce conformational constraints into peptide analogs, enhancing their stability and biological activity.
• Medicinal Chemistry: Acts as a precursor for the development of proline and glutamic acid analogs with potential therapeutic applications.
• Chemical Biology: Employed as a tool compound or probe to study enzyme mechanisms and protein-ligand interactions.
• Academic & Industrial R&D: Utilized in exploratory synthetic chemistry for the construction of novel heterocyclic libraries.

Basic Information

Product Name	2,3-Methanopyroglutamic Acid
CAS No.	116447-40-6
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	(3aS,7aR)-Hexahydro-1H-pyrrolo[1,2-c]oxazole-1,3-dione; (3aS,7aR)-Octahydropyrrolo[1,2-c]oxazole-1,3-dione; 2,3-Methano-L-pyroglutamic Acid; (3aS,7aR)-1,3-Dioxooctahydro-1H-pyrrolo[1,2-c]oxazole; L-2,3-Methanopyroglutamic Acid
EINECS	Contact for details

Quality Control

Our 2,3-Methanopyroglutamic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.